mirror of
https://github.com/GenderDysphoria/GenderDysphoria.fyi.git
synced 2025-01-30 23:06:18 +00:00
Structure for Spanish pretty much done
This commit is contained in:
G. Queiroz
parent
e201ac129a
commit
1b2208ae5b
@ -32,4 +32,37 @@ module.exports = exports = [
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preBody: '_disclaimer',
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},
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},
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{
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output: 'public/gdb/es/imprimible.md',
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sources: [
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'public/gdb/es/index.md',
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'public/gdb/es/que-es-el-genero.md',
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'public/gdb/es/historia.md',
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'public/gdb/es/euforia.md',
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'public/gdb/es/disforia-fisica.md',
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'public/gdb/es/disforia-bioquimica.md',
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'public/gdb/es/disforia-social.md',
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'public/gdb/es/disforia-societal.md',
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'public/gdb/es/disforia-sexual.md',
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'public/gdb/es/disforia-de-presentacion.md',
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'public/gdb/es/disforia-historica.md',
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'public/gdb/es/disforia-gestionada.md',
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'public/gdb/es/sindrome-del-impostor.md',
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'public/gdb/es/diagnosticos.md',
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'public/gdb/es/tratamiento.md',
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'public/gdb/es/causas.md',
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'public/gdb/es/cromosomas.md',
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'public/gdb/es/hormonas.md',
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'public/gdb/es/segunda-pubertad-masc.md',
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'public/gdb/es/segunda-pubertad-fem.md',
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'public/gdb/es/conclusion.md',
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],
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meta: {
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title: 'La Biblia de la Disforia de Género',
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lang: 'es',
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description: 'Un clavado a las multitudes de formas en que se manifiesta la disforia de género y lo que significa ser transgénero.',
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classes: [ 'gdb', 'longform' ],
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preBody: '_declaracion',
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},
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},
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];
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27
public/_gdb-en-menu.hbs
Normal file
27
public/_gdb-en-menu.hbs
Normal file
@ -0,0 +1,27 @@
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<div class="dropdown-menu" aria-labelledby="nav-gdb">
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<a href="/gdb/printable" class="{{#is meta.url '/gdb/printable' }}active {{/is}}dropdown-item">View All</a>
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<a href="/gdb.pdf" class="dropdown-item">Download PDF {{icon 'pdf' size="1em" style="vertical-align:middle;margin-bottom:3px;"}} </a>
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<hr class="dropdown-divider">
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<a href="/gdb/" class="{{#is meta.url '/gdb/index' '/' }}active {{/is}}dropdown-item">Introduction</a>
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<a href="/gdb/what-is-gender" class="{{#is meta.url '/gdb/what-is-gender' }}active {{/is}}dropdown-item">What is Gender?</a>
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<a href="/gdb/history" class="{{#is meta.url '/gdb/history' }}active {{/is}}dropdown-item">The History of Gender Dysphoria</a>
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<a href="/gdb/euphoria" class="{{#is meta.url '/gdb/euphoria' }}active {{/is}}dropdown-item">Gender Euphoria</a>
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<a href="/gdb/physical-dysphoria" class="{{#is meta.url '/gdb/physical-dysphoria' }}active {{/is}}dropdown-item">Physical Dysphoria</a>
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<a href="/gdb/biochemical-dysphoria" class="{{#is meta.url '/gdb/biochemical-dysphoria' }}active {{/is}}dropdown-item">Biochemical Dysphoria</a>
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<a href="/gdb/social-dysphoria" class="{{#is meta.url '/gdb/social-dysphoria' }}active {{/is}}dropdown-item">Social Dysphoria</a>
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<a href="/gdb/societal-dysphoria" class="{{#is meta.url '/gdb/societal-dysphoria' }}active {{/is}}dropdown-item">Societal Dysphoria</a>
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<a href="/gdb/sexual-dysphoria" class="{{#is meta.url '/gdb/sexual-dysphoria' }}active {{/is}}dropdown-item">Sexual Dysphoria</a>
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<a href="/gdb/presentational-dysphoria" class="{{#is meta.url '/gdb/presentational-dysphoria'}}active {{/is}}dropdown-item">Presentational Dysphoria</a>
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<a href="/gdb/existential-dysphoria" class="{{#is meta.url '/gdb/existential-dysphoria' }}active {{/is}}dropdown-item">Existential Dysphoria</a>
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<a href="/gdb/managed-dysphoria" class="{{#is meta.url '/gdb/managed-dysphoria' }}active {{/is}}dropdown-item">Managed Dysphoria</a>
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<a href="/gdb/impostor-syndrome" class="{{#is meta.url '/gdb/impostor-syndrome' }}active {{/is}}dropdown-item">Impostor Syndrome</a>
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<a href="/gdb/diagnoses" class="{{#is meta.url '/gdb/diagnoses' }}active {{/is}}dropdown-item">Clinical Diagnoses</a>
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<a href="/gdb/treatment" class="{{#is meta.url '/gdb/treatment' }}active {{/is}}dropdown-item">Treating Gender Dysphoria</a>
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<a href="/gdb/causes" class="{{#is meta.url '/gdb/causes' }}active {{/is}}dropdown-item">Causes of Gender Dysphoria</a>
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<a href="/gdb/chromosomes" class="{{#is meta.url '/gdb/chromosomes' }}active {{/is}}dropdown-item">Chromosomes</a>
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<a href="/gdb/hormones" class="{{#is meta.url '/gdb/hormones' }}active {{/is}}dropdown-item">How Hormones Work</a>
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<a href="/gdb/second-puberty-masc" class="{{#is meta.url '/gdb/second-puberty-masc' }}active {{/is}}dropdown-item">Androgenic Second Puberty 101</a>
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<a href="/gdb/second-puberty-fem" class="{{#is meta.url '/gdb/second-puberty-fem' }}active {{/is}}dropdown-item">Estrogenic Second Puberty 101</a>
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<a href="/gdb/conclusion" class="{{#is meta.url '/gdb/conclusion' }}active {{/is}}dropdown-item">Conclusion</a>
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</div>
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27
public/_gdb-es-menu.hbs
Normal file
27
public/_gdb-es-menu.hbs
Normal file
@ -0,0 +1,27 @@
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<div class="dropdown-menu" aria-labelledby="nav-gdb">
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<a href="/gdb/es/imprimible" class="{{#is meta.url '/gdb/es/imprimible' }}active {{/is}}dropdown-item">Ver Todo</a>
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<!-- <a href="/gdb.es.pdf" class="dropdown-item">Descargar PDF {{icon 'pdf' size="1em" style="vertical-align:middle;margin-bottom:3px;"}} </a> -->
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<hr class="dropdown-divider">
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<a href="/gdb/es/" class="{{#is meta.url '/gdb/es/index' '/' }}active {{/is}}dropdown-item">Introducción</a>
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<a href="/gdb/es/que-es-el-genero" class="{{#is meta.url '/gdb/es/que-es-el-genero' }}active {{/is}}dropdown-item">¿Qué es el Género?</a>
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<a href="/gdb/es/historia" class="{{#is meta.url '/gdb/es/historia' }}active {{/is}}dropdown-item">La Historia de la Disforia de Género</a>
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<a href="/gdb/es/euforia" class="{{#is meta.url '/gdb/es/euforia' }}active {{/is}}dropdown-item">Euforia de Género</a>
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<a href="/gdb/es/disforia-fisica" class="{{#is meta.url '/gdb/es/disforia-fisica' }}active {{/is}}dropdown-item">Disforia de Género Física</a>
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<a href="/gdb/es/disforia-bioquimica" class="{{#is meta.url '/gdb/es/disforia-bioquimica' }}active {{/is}}dropdown-item">Disforia Bioquímica</a>
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<a href="/gdb/es/disforia-social" class="{{#is meta.url '/gdb/es/disforia-social' }}active {{/is}}dropdown-item">Disforia Social</a>
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<a href="/gdb/es/disforia-societal" class="{{#is meta.url '/gdb/es/disforia-societal' }}active {{/is}}dropdown-item">Disforia Societal</a>
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<a href="/gdb/es/disforia-sexual" class="{{#is meta.url '/gdb/es/disforia-sexual' }}active {{/is}}dropdown-item">Disforia Sexual</a>
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<a href="/gdb/es/disforia-de-presentacion" class="{{#is meta.url '/gdb/es/disforia-de-presentacion'}}active {{/is}}dropdown-item">Disforia de Presentación</a>
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<a href="/gdb/es/disforia-historica" class="{{#is meta.url '/gdb/es/disforia-historica' }}active {{/is}}dropdown-item">Disforia Histórica</a>
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<a href="/gdb/es/disforia-gestionada" class="{{#is meta.url '/gdb/es/disforia-gestionada' }}active {{/is}}dropdown-item">Disforia Gestionada</a>
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<a href="/gdb/es/sindrome-del-impostor" class="{{#is meta.url '/gdb/es/sindrome-del-impostor' }}active {{/is}}dropdown-item">Síndrome del Impostor</a>
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<a href="/gdb/es/diagnosticos" class="{{#is meta.url '/gdb/es/diagnosticos' }}active {{/is}}dropdown-item">Clinical Diagnoses</a>
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<a href="/gdb/es/tratamiento" class="{{#is meta.url '/gdb/es/tratamiento' }}active {{/is}}dropdown-item">Treating Gender Dysphoria</a>
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<a href="/gdb/es/causas" class="{{#is meta.url '/gdb/es/causas' }}active {{/is}}dropdown-item">Causes of Gender Dysphoria</a>
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<a href="/gdb/es/cromosomas" class="{{#is meta.url '/gdb/es/cromosomas' }}active {{/is}}dropdown-item">Cromosomas</a>
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<a href="/gdb/es/hormonas" class="{{#is meta.url '/gdb/es/hormonas' }}active {{/is}}dropdown-item">Cómo Funcionan las Hormonas</a>
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<a href="/gdb/es/segunda-pubertad-masc" class="{{#is meta.url '/gdb/es/segunda-pubertad-masc' }}active {{/is}}dropdown-item">Intro. Segunda Pubertad Androgénica</a>
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<a href="/gdb/es/segunda-pubertad-fem" class="{{#is meta.url '/gdb/es/segunda-pubertad-fem' }}active {{/is}}dropdown-item">Intro. Segunda Pubertad Estrogénica</a>
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<a href="/gdb/es/conclusion" class="{{#is meta.url '/gdb/es/conclusion' }}active {{/is}}dropdown-item">Conclusión</a>
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</div>
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@ -1,27 +1,5 @@
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<div class="dropdown-menu" aria-labelledby="nav-gdb">
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<a href="/gdb/printable" class="{{#is meta.url '/gdb/printable' }}active {{/is}}dropdown-item">View All</a>
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<a href="/gdb.pdf" class="dropdown-item">Download PDF {{icon 'pdf' size="1em" style="vertical-align:middle;margin-bottom:3px;"}} </a>
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<hr class="dropdown-divider">
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<a href="/gdb/" class="{{#is meta.url '/gdb/index' '/' }}active {{/is}}dropdown-item">Introduction</a>
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<a href="/gdb/what-is-gender" class="{{#is meta.url '/gdb/what-is-gender' }}active {{/is}}dropdown-item">What is Gender?</a>
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<a href="/gdb/history" class="{{#is meta.url '/gdb/history' }}active {{/is}}dropdown-item">The History of Gender Dysphoria</a>
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<a href="/gdb/euphoria" class="{{#is meta.url '/gdb/euphoria' }}active {{/is}}dropdown-item">Gender Euphoria</a>
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<a href="/gdb/physical-dysphoria" class="{{#is meta.url '/gdb/physical-dysphoria' }}active {{/is}}dropdown-item">Physical Dysphoria</a>
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<a href="/gdb/biochemical-dysphoria" class="{{#is meta.url '/gdb/biochemical-dysphoria' }}active {{/is}}dropdown-item">Biochemical Dysphoria</a>
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<a href="/gdb/social-dysphoria" class="{{#is meta.url '/gdb/social-dysphoria' }}active {{/is}}dropdown-item">Social Dysphoria</a>
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<a href="/gdb/societal-dysphoria" class="{{#is meta.url '/gdb/societal-dysphoria' }}active {{/is}}dropdown-item">Societal Dysphoria</a>
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<a href="/gdb/sexual-dysphoria" class="{{#is meta.url '/gdb/sexual-dysphoria' }}active {{/is}}dropdown-item">Sexual Dysphoria</a>
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<a href="/gdb/presentational-dysphoria" class="{{#is meta.url '/gdb/presentational-dysphoria'}}active {{/is}}dropdown-item">Presentational Dysphoria</a>
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<a href="/gdb/existential-dysphoria" class="{{#is meta.url '/gdb/existential-dysphoria' }}active {{/is}}dropdown-item">Existential Dysphoria</a>
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<a href="/gdb/managed-dysphoria" class="{{#is meta.url '/gdb/managed-dysphoria' }}active {{/is}}dropdown-item">Managed Dysphoria</a>
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<a href="/gdb/impostor-syndrome" class="{{#is meta.url '/gdb/impostor-syndrome' }}active {{/is}}dropdown-item">Impostor Syndrome</a>
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<a href="/gdb/diagnoses" class="{{#is meta.url '/gdb/diagnoses' }}active {{/is}}dropdown-item">Clinical Diagnoses</a>
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<a href="/gdb/treatment" class="{{#is meta.url '/gdb/treatment' }}active {{/is}}dropdown-item">Treating Gender Dysphoria</a>
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<a href="/gdb/causes" class="{{#is meta.url '/gdb/causes' }}active {{/is}}dropdown-item">Causes of Gender Dysphoria</a>
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<a href="/gdb/chromosomes" class="{{#is meta.url '/gdb/chromosomes' }}active {{/is}}dropdown-item">Chromosomes</a>
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<a href="/gdb/hormones" class="{{#is meta.url '/gdb/hormones' }}active {{/is}}dropdown-item">How Hormones Work</a>
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<a href="/gdb/second-puberty-masc" class="{{#is meta.url '/gdb/second-puberty-masc' }}active {{/is}}dropdown-item">Androgenic Second Puberty 101</a>
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<a href="/gdb/second-puberty-fem" class="{{#is meta.url '/gdb/second-puberty-fem' }}active {{/is}}dropdown-item">Estrogenic Second Puberty 101</a>
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<a href="/gdb/conclusion" class="{{#is meta.url '/gdb/conclusion' }}active {{/is}}dropdown-item">Conclusion</a>
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</div>
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{{#is page.lang "es"}}
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<a href="/gdb/" class="top-nav-item dropdown-toggle" id="nav-gdb" data-toggle="dropdown" data-flip="false" aria-haspopup="true" aria-expanded="false">La Biblia de la Disforia de Género</a>{{import '/public/_gdb-es-menu'}}
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{{else}}
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<a href="/gdb/" class="top-nav-item dropdown-toggle" id="nav-gdb" data-toggle="dropdown" data-flip="false" aria-haspopup="true" aria-expanded="false">The Gender Dysphoria Bible</a>{{import '/public/_gdb-en-menu'}}
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{{/is}}
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@ -15,9 +15,9 @@ tweets:
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- https://twitter.com/LisaTMullin/status/1224043995413639168
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- https://twitter.com/LisaTMullin/status/1224044949160611840
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siblings:
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prev: /gdb/treatment
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prev: /gdb/es/tratamiento
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prevCaption: Treating Gender Dysphoria
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next: /gdb/chromosomes
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next: /gdb/es/chromosomas
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nextCaption: But... but... the chromosomes!
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---
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@ -7,10 +7,10 @@ preBody: '_declaracion'
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classes:
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- gdb
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siblings:
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prev: /gdb/causes
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prev: /gdb/es/causas
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prevCaption: Causes of Gender Dysphoria
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next: /gdb/conclusion
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nextCaption: Conclusion
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next: /gdb/es/hormonas
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nextCaption: Hormones
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tweets:
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- https://twitter.com/RebeccaRHelm/status/1207834357639139328
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- https://twitter.com/RebeccaRHelm/status/1207835110617309191
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@ -4,7 +4,7 @@ lang: "es"
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title: "In Conclusion"
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description: "Enough with the gatekeeping already."
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siblings:
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prev: /gdb/chromosomes
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prev: /gdb/es/chromosomas
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prevCaption: Disorders of Sexual Development
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classes:
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- gdb
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95
public/gdb/es/cromosomas.md
Normal file
95
public/gdb/es/cromosomas.md
Normal file
@ -0,0 +1,95 @@
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---
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date: "2020-01-26T20:41:55.827Z"
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title: "Disorders of Sex Development: Gender is not Chromosomal"
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linkTitle: "Chromosomes"
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description: "DNA is more what you'd call guidelines, than actual rules."
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preBody: '_disclaimer'
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classes:
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- gdb
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siblings:
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prev: /gdb/causes
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prevCaption: Causes of Gender Dysphoria
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next: /gdb/hormones
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nextCaption: How Hormones Work
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tweets:
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- https://twitter.com/RebeccaRHelm/status/1207834357639139328
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- https://twitter.com/RebeccaRHelm/status/1207835110617309191
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- https://twitter.com/RebeccaRHelm/status/1207835384358604802
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- https://twitter.com/RebeccaRHelm/status/1207835597206937600
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- https://twitter.com/RebeccaRHelm/status/1207835815071473664
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- https://twitter.com/RebeccaRHelm/status/1207835999130259456
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- https://twitter.com/RebeccaRHelm/status/1207837155667718145
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- https://twitter.com/RebeccaRHelm/status/1207838570276372480
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- https://twitter.com/RebeccaRHelm/status/1207838924263084033
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- https://twitter.com/RebeccaRHelm/status/1207839452619522048
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- https://twitter.com/RebeccaRHelm/status/1207839986801922048
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- https://twitter.com/alicemiriel/status/1208181235593490433
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- https://twitter.com/TransEthics/status/1223942625708761088
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---
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# But the Chromosomes!!!
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{!{ <div class="gutter">
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{{import '~/tweet' ids=[
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'1223942625708761088'
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] tweets=meta.tweets className="" }}
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</div>}!}
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There are dozens of ways that chromosomes can be much more complex than XX and XY. Medically these are referred to as DSDs ([Disorders of Sex Development](https://en.wikipedia.org/wiki/Disorders_of_sex_development)). Not all result in an intersex condition, and many only manifest at the onset of puberty.
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- [De la Chapelle Syndrome](https://en.wikipedia.org/wiki/XX_male_syndrome) (46,XX Male) occurs when the SRY gene from the sperm parent crosses over into a non-Y-bearing sperm during spermatogenesis. When the egg and sperm merge, it results in an XX embryo with an SRY gene, creating a phenotypical male child with two X chromosomes.
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- [Swyer Syndrome](https://en.wikipedia.org/wiki/Swyer_syndrome) (46,XY Female) produces a phenotypically female child with an XY chromosome. This results from a dozen different genetic conditions, including:
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- Absence or defect of an SRY gene
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- Absence or defect of [DHH](https://en.wikipedia.org/wiki/Desert_hedgehog_(protein)) synthesis
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- Absence of the [SF-1](https://en.wikipedia.org/wiki/Steroidogenic_factor_1) protein due to adrenal failure
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- Absence of or defect the [CBX2](https://en.wikipedia.org/wiki/CBX2_(gene)) gene, preventing TDF cascade
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- [XX Gonadal Dysgenesis](https://en.wikipedia.org/wiki/XX_gonadal_dysgenesis) is very similar to Swyer Syndrome, except occurs in XX children and results in nonfunctional ovaries.
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- [Turner Syndrome](https://en.wikipedia.org/wiki/Turner_syndrome) (45,X) produces a phenotypically female child with numerous abnormalities. It occurs when neither an X or Y chromosome crosses over from the sperm.
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- [Klinefelter Syndrome](https://en.wikipedia.org/wiki/Klinefelter_syndrome) (47,XXY) results in a phenotypically male child with more feminine traits. In extremely rare cases [it appears in female assigned children](https://www.ncbi.nlm.nih.gov/pubmed/15755052) as well, resulting in feminized testicles instead of ovaries.
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- [49,XXXXY Klinefelter Syndrome](https://en.wikipedia.org/wiki/49,XXXXY) is often fatal, but when it isn't, it will always results in a sterile child.
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- [Trisomy X](https://en.wikipedia.org/wiki/Triple_X_syndrome) (47,XXX), [Tetrasomy X](https://en.wikipedia.org/wiki/Tetrasomy_X) (48,XXXX), and [Pentasomy X](https://en.wikipedia.org/wiki/49,_XXXXX) (49,XXXXX) all result in a female child, but with progressively more intense health issues.
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- [XXYY Syndrome](https://en.wikipedia.org/wiki/XXYY_syndrome) results in male children (due to two SRY genes) which often experience hypogonadism, needing testosterone supplements, but otherwise seeming like a typical male
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- [Mosaicism](https://en.wikipedia.org/wiki/Mosaic_(genetics)) results when some cells in the body have one set of chromosomes and other cells have another due to a mutation of the genome during gestation. This may be XX/XY (resulting in a dual set of genitalia), X/XY (a milder form of Swyer or Turner syndromes) or XX/XXY (a milder form of Klinefelter syndrome).
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- [Chimerism](https://en.wikipedia.org/wiki/Chimera_(genetics)) occurs when two fertilized embryos merge together into one zygote, causing half of the child to contain one set of DNA and the other half to contain another. This can result in an otherwise completely typical human being of either male or female phenotype, even capable of producing offspring, but which comes back on a kareotype test as not matching their phenotype based on where the sample was taken on their body. In extremely rare cases this can result in two full sets of reproductive organs.
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|
||||
- [Congenital Adrenal Hyperplasia](https://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia)(CAH) is masculinization of the female genitals in an XX child due to overactive adrenal glands.
|
||||
|
||||
- [Androgen Insensitivity Syndrome](https://en.wikipedia.org/wiki/Androgen_insensitivity_syndrome)(AIS) is a total or partial resistance to all androgens, preventing masculinization of all organs, save for the testicles, in an XY child. AIS subjects typically develop a female gender identity, but some partial cases may be male.
|
||||
|
||||
- [5-alpha-reductase deficiency](https://en.wikipedia.org/wiki/5-alpha-reductase_deficiency)(5ARD) is a failure in the body's ability to metabolize testosterone into dihydrotestosterone (DHT), preventing masculinization of the genitalia until the onset of puberty, when the child suddenly grows a penis.
|
||||
|
||||
- [Aromatase Deficiency](https://en.wikipedia.org/wiki/Aromatase_deficiency) causes masculinization of an otherwise female child due to excess levels of testosterone (and can bleed-over into the mother during gestation).
|
||||
|
||||
- [Aromatase Excess](https://en.wikipedia.org/wiki/Aromatase_excess_syndrome) causes feminization in an otherwise male child, as all testosterone is converted into estrogen.
|
||||
|
||||
{!{ <div class="span34 center print-span2">
|
||||
{{import '~/tweet' ids=[
|
||||
'1207834357639139328'
|
||||
'1207835110617309191'
|
||||
'1207835384358604802'
|
||||
'1207835597206937600'
|
||||
'1207835815071473664'
|
||||
'1207835999130259456'
|
||||
'1207837155667718145'
|
||||
'1207838570276372480'
|
||||
'1207839986801922048'
|
||||
'1207838924263084033'
|
||||
'1207839452619522048'
|
||||
] tweets=meta.tweets className="oneblock" }}
|
||||
{{import '~/tweet' ids=[
|
||||
'1208181235593490433'
|
||||
] tweets=meta.tweets className="" }}
|
||||
</div>}!}
|
||||
120
public/gdb/es/hormonas.md
Normal file
120
public/gdb/es/hormonas.md
Normal file
@ -0,0 +1,120 @@
|
||||
---
|
||||
date: "2020-01-26T20:41:55.827Z"
|
||||
title: "Hormones: How do they work"
|
||||
linkTitle: "How Hormones Work"
|
||||
description: "It's nothing like magnets."
|
||||
preBody: '_disclaimer'
|
||||
siblings:
|
||||
prev: /gdb/es/chromosomas
|
||||
prevCaption: Chromosomes
|
||||
next: /gdb/es/segunda-pubertad-masc
|
||||
nextCaption: Androgenic Second Puberty
|
||||
classes:
|
||||
- gdb
|
||||
---
|
||||
|
||||
# How Hormones Work
|
||||
|
||||
As we described in the [Causes of Gender Dysphoria](/gdb/causes) section, every human's DNA contains the genetic instructions for both male and female bodies, and which set of instructions gets used is controlled by what hormones your gonads produce. That differentiation occurs entirely based on whether you happen to have an SRY gene which, in the 6-8th week of gestation, kicks off a chain reaction that produces testes instead of ovaries. From that point on, every sexual attribute of the human body (primary and secondary) is a result of the hormones that those gonads produce.
|
||||
|
||||
If they produce estrogens (primarily Estradiol) then the genitals form into a vulva, vagina and uterus. If they produce androgens (primarily Testosterone) then the genitals form into a penis and scrotum, shifting the [Skene's gland](https://en.wikipedia.org/wiki/Skene%27s_gland) downward and enlarging it into a prostate. Differentiation ends here until the onset of puberty, 9-10 years later, and we all know what puberty does.
|
||||
|
||||
So how does this work? Why do the cells differentiate like this? Well, before we can explain that, first we have to explain the concept of a **Receptor**.
|
||||
|
||||
|
||||
## Hormone Receptors
|
||||
|
||||
In simplest terms, a receptor is like the keyed lock ignition on a car (do new car’s still have keyed ignitions?). Every cell in the body has a set of locks which activate different functions within that cell. They’re like switches which signal to the cell that it should activate a different part of its genetic sequence. Each receptor can only accept certain chemical compounds, much like how a lock can only accept certain keys, and different chemicals have different capabilities at turning the key. Some can completely start the car, while others only turn it to Accessory Mode.
|
||||
|
||||
The ability for a chemical to fit into a receptor is called **Relational Binding Affinity**, and is measured as percentage of how likely a chemical will bind to a receptor compared to another. So, for example, if Hormone B binds only 10% of the time in relation to Hormone A, then it is said to have a 10% binding affinity. Similarly, the ability for a chemical to turn the key is called *Transactivational Ability*. Compounds which fit into a receptor but don’t do anything are called *Antagonists*, compounds which are able to turn the key are called **Agonists**. If it can only turn the key a tiny bit, it’s called a **Partial Agonist**.
|
||||
|
||||
You can think of antagonists like bouncers at a club. They stand in the doorway and prevent anything else from getting through, but don’t enter the club themselves. Most antagonists are referred to as **blockers**. This is different from an **inhibitor**, which is a compound that slows down a chemical reaction, or an *activator*, which speeds up a reaction. In receptors, an inhibitor lowers the ability of the receptor, causing it to respond less effectively to things that bind to the receptor, and an activator increases the ability of the receptor, making it respond stronger, like a booster.
|
||||
|
||||
In some cases a hormone can function as an inhibitor or an activator for a different hormone by slowing down or increasing behavior in a cell. For example, progesterone increase cell activity, making cells respond more effectively to estrogens and androgens, and testosterone increases the transaction ability of dopamine receptors, so less dopamine is needed in the brain for the same effect.
|
||||
|
||||
## Whats in a Hormone
|
||||
|
||||
There are four main kinds of hormones:
|
||||
|
||||
- [Amino Acids](https://en.wikipedia.org/wiki/Amino_acid) such as Melatonin which controls sleep, or Thyroxine which regulates the metabolism.
|
||||
- [Peptides](https://en.wikipedia.org/wiki/Peptide_hormone), like Oxytocin and Insulin, which are collections of Amino Acids.
|
||||
- [Eicosanoids](https://en.wikipedia.org/wiki/Eicosanoid) that are formed from lipids and fatty acids and predominantly affect the immune system
|
||||
- [Steroids](https://en.wikipedia.org/wiki/Steroid) are signaling molecules produced by various internal organs in order to pass messages to other organs within the body.
|
||||
|
||||
{!{ <div class="gutter print-span3">{{import '~/img' images.steroidogenesis
|
||||
className="card"
|
||||
link="https://en.wikipedia.org/wiki/File:Steroidogenesis.svg"
|
||||
external=1
|
||||
alt="Chart of steroid metabolism flow"
|
||||
caption="All steroids are formed from cholesterols (top left) and are derived from other steroids. Progestins form into Androgens which form into Estrogens. This is a one-way exchange, and does not reverse, so don't believe it when someone tells you that too much estrogen will turn it into testosterone."
|
||||
}}</div> }!}
|
||||
|
||||
For the purposes of transition, this last category is what we care about the most, as all of the sex hormones are steroids. They fall into seven main categories:
|
||||
|
||||
- [Androgens](https://en.wikipedia.org/wiki/Androgen)
|
||||
- [Estrogens](https://en.wikipedia.org/wiki/Estrogen)
|
||||
- [Progestagins](https://en.wikipedia.org/wiki/Progestogen)
|
||||
- [Glucocorticoids](https://en.wikipedia.org/wiki/Glucocorticoid)
|
||||
- [Mineralcorticoids](https://en.wikipedia.org/wiki/Mineralocorticoid)
|
||||
- [Neurosteroids](https://en.wikipedia.org/wiki/Steroid)
|
||||
- [Aminosteroids](https://en.wikipedia.org/wiki/Aminosteroid)
|
||||
|
||||
The first three of these are what we care about most when it comes to Hormone Therapy. Note: All human beings, regardless of phenotype, have some of every one of these hormones in their bodies. The ratios are what affect body shape.
|
||||
|
||||
|
||||
### Androgens
|
||||
|
||||
There are nearly a dozen different androgens, but the ones we care about the most are [Testosterone](https://en.wikipedia.org/wiki/Testosterone) and [Dihydrotestosterone](https://en.wikipedia.org/wiki/Dihydrotestosterone).
|
||||
|
||||
Testosterone is the primary masculinizing hormone for the human body and is produced in the adrenal glands, the testes, and in the ovaries (where it is immediately converted into estrone and estradiol). It tells both muscle and bone cells to grow and in higher concentrations encourages larger muscle mass and thicker skeletal structure. This also means that Testosterone is critical for bone health, as it affects calcium distribution within the skeletal structure. Thus, severe depletion of testosterone can result in osteoperosis and fragile bones. Testosterone also plays a major role in sex drive and libido, encouraging mating behavior within the cerebral cortex.
|
||||
|
||||
Dihydrotestosterone (DHT), which is converted from Testosterone in the prostate, skin and liver, plays a major role in the development of the male genitalia during puberty by inducing random erections, and the growth of facial and body hair. Paradoxically, DHT is also what causes male pattern baldness, as it chokes off blood circulation to the follicles on the top of the scalp (sorry, trans guys, it's a double edged sword). DHT binds to androgen receptors ten times more strongly than testosterone, which is why it is critical to eliminate it for feminizing transition.
|
||||
|
||||
|
||||
### Estrogens
|
||||
|
||||
There are four estrogens: [Estradiol](https://en.wikipedia.org/wiki/Estradiol), [Estrone](https://en.wikipedia.org/wiki/Estrone), Estriol and Estetrol. The latter two are only produced during pregnancy and are important for fetal health, but have no bearing on transition.
|
||||
|
||||
Estradiol is the Feminizing hormone, as it is the primary signaling hormone for growth in the mammary glands (breast tissue), and because it encourages fat deposits in the thighs, hips, butt, chest and arms, while discouraging fat deposits in the abdomen, thus producing a curvier figure. Estradiol also promote increased collagen production, resulting in softer skin and more flexible tendons & ligaments.
|
||||
|
||||
Estrone's role in the body has been something of a puzzle in medical research, as it has significantly lower binding affinity compared to estradiol (0.6%) and very low transactivational ability (4%). The hormone doesn't appear to *do* anything, it just sits in the blood stream. However it has a unique ability to convert to and from Estradiol via an enzyme group called [17β-HSD](https://en.wikipedia.org/wiki/17%CE%B2-Hydroxysteroid_dehydrogenase), making it ideally suited to function like an estrogen battery within the body.
|
||||
|
||||
New research is starting to suggest that the body may regulate total estradiol levels by releasing HSD17B1 to turn estradiol into estrone, and releasing HSD17B2 to convert it back, however this is very early study. Both enzymes are produced in breast tissue, and may play a role in the presence of cyclical period-like symptoms in estrogenic individuals who do not have ovaries, such as trans women.
|
||||
|
||||
{!{ <div class="gutter"><div class="card"><div class="card-body"><h4 class="card-title">For Your Information</h4> }!}
|
||||
|
||||
**Why aren't AFAB trans people prescribed estrogen blockers alongside testosterone?**
|
||||
|
||||
There are two separate sources for estrogens within the female reproductive system. Ovaries contains thousands of follicles, cell structures which produce eggs. The pituitary gland produces luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which encourages the follicles to grow into luteal cells. Theca cells within the follicle produce testosterone, and granulosa cells produce the enzyme [aromatase](https://en.wikipedia.org/wiki/Aromatase), which converts that testosterone into estradiol. This is the first source of estrogen, but it is not the largest source.
|
||||
|
||||
Note: This is why PCOS causes ovaries to produce testosterone; the ovarian cysts disrupt the aromatase production, so the testosterone does not get converted.
|
||||
|
||||
Two weeks into the period cycle the hypothalamus tells the pituitary gland to produce an LH and FSH spike three to four times stronger than earlier in the cycle. That surge causes the follicles to swell until one pops, releasing an egg, at which point the remains of the follicle become a structure known as the corpus luteum. That corpus luteum then begins to produce progesterone and significantly more estrogens in order to prepare the womb for a fertilized egg. This is the second source.
|
||||
|
||||
Taking testosterone causes the hypothalamus to deactivate the genes that initiate this LH and FSH spike, so the follicles never reach maturity, ovulation never occurs, and the corpus luteum is never formed, removing a significant source of estrogen within the ovaries.
|
||||
|
||||
*So no, Reddit, it isn't just "because testosterone is stronger", it's because ovaries are a hell of a lot more complex than testes and are easier to disrupt. Please stop spreading this falsehood.*
|
||||
|
||||
{!{ </div></div></div> }!}
|
||||
|
||||
### Progestagins
|
||||
|
||||
The primary progestogin is [progesterone](https://en.wikipedia.org/wiki/Progesterone), which plays numerous roles in the body and has been found to be [an important component for feminizing hormone therapy](https://academic.oup.com/jcem/article/104/4/1181/5270376).
|
||||
|
||||
One of the largest roles that the progestogin receptor plays is in the regulation of gonadal function (ovaries and testies). The hypothalamus is positively *littered* with progestogin receptors and responds strongly to their activation, downregulating the production of [GnRH](https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone), which then reduces the production of [luteinizing hormone](https://en.wikipedia.org/wiki/Luteinizing_hormone) by the pituitary gland.
|
||||
|
||||
LH is what tells the ovaries and testes to produce estrogen and androgens. LH and its sibling hormone [FSH](https://en.wikipedia.org/wiki/Follicle-stimulating_hormone) both play central roles in ovulation, which is another large source of estrogen in ovary-havers. Thus, synthetic progestins, chemicals that fit into progestogin receptors, are often included in birth control in order to prevent ovulation. In AMABs, progestogins are a useful tool for blocking testosterone production.
|
||||
|
||||
Another type of cell that is full of progestogin receptors is mammary tissue. Progesterone plays a major role in the growth and maturation of milk ducts within breast tissue. While little formal research has been conducted into progesterone's effect on breast development, anecdotally it has been seen widely across the transfem community to provide significant improvements in breast fullness. Progesterone has also been demonstrated to increase blood flow to breast tissue, and encourages fat deposits in the breasts, both of which increase breast size.
|
||||
|
||||
Additionally, progesterone promotes better sleep, improves cardiovascular health, increases ketogenesis (reducing triglycerides), increases metabolic function, and has been found to reduce breast cancer risk.
|
||||
|
||||
### Mineralcorticoids
|
||||
|
||||
Mineralcorticoids play no role in transition, but they are worth mentioning because of one major hormone: [Aldosterone](https://en.wikipedia.org/wiki/Aldosterone).
|
||||
|
||||
Aldosterone is what instructs the kidneys to *stop* extracting water from the blood stream. It is produced by the adrenal glands in order to regulate body hydration. Why is this significant?
|
||||
|
||||
Because one drug that is very commonly used in trans hormone therapy is an extremely powerful aldosterone antagonist... Spironolactone. Spiro binds to mineralcorticoid receptors more strongly than aldosterone does, but does not activate the receptor. It just clogs it, preventing the kidneys from receiving the signal to stop extracting water.
|
||||
|
||||
This is why spiro makes people pee so much.
|
||||
267
public/gdb/es/segunda-pubertad-fem.md
Normal file
267
public/gdb/es/segunda-pubertad-fem.md
Normal file
@ -0,0 +1,267 @@
|
||||
---
|
||||
date: "2020-01-26T20:41:55.827Z"
|
||||
title: "Estrogenic Second Puberty 101"
|
||||
description: "What to expect from feminizing HRT"
|
||||
preBody: '_disclaimer'
|
||||
siblings:
|
||||
prev: /gdb/es/segunda-pubertad-masc
|
||||
prevCaption: Androgenic Second Puberty
|
||||
next: /gdb/es/conclusion
|
||||
nextCaption: Conclusion
|
||||
classes:
|
||||
- gdb
|
||||
---
|
||||
|
||||
# Estrogenic Second Puberty 101
|
||||
|
||||
## What to expect from Feminizing HRT
|
||||
|
||||
This is a compilation of reported medical transition changes collected from testimonials of AMAB trans people taking estrogen based hormone therapy. This information is gathered from social media and chat rooms. Yes, that means this is all anecdotal, but historically, most of transgender medical study is anecdotal because no one wants to fund transgender medical research.
|
||||
|
||||
**Note that this is a list of _possible_ changes. There is no guarantee that every person on feminizing HRT will experience all of these. Your age, genetics, medical history, degree of masculinization from natal puberty, and hormone regimen can all have impacts on results. There is also just a degree of randomness -- every body is different -- and some things can take years to appear.**
|
||||
|
||||
### Breast Growth
|
||||
|
||||
Despite public perceptions, the majority of transfems do not pursue breast augmentation, as it often isn't necessary (and for many, is not within reach). Every human is born with breast tissue, it simply remains inactive without estrogen to make it grow. Development typically takes 2-5 years, but can continue for more than ten years, just as it does for cisgender women.
|
||||
|
||||
Expect aches and pains in the chest, along with lots of tenderness, in the area surrounding and behind the areola. Avoid bumping into anything, as it *will* hurt. Nipples and areolas will become much more sensitive while also becoming larger and darker. You'll want to invest in some sports bras.
|
||||
|
||||
This may be accompanied with lactation. Some secretion is normal and can be expected as milk ducts form and open up, so there is no cause for alarm. However, significant discharge without intentional stimulation may be a sign of a prolactin imbalance, so you should tell your doctor if this happens.
|
||||
|
||||
### Skin Softening
|
||||
|
||||
Testosterone promotes the thickening and toughening of the epidermis, so removing it makes the skin thinner. Additionally, estrogen promotes the production of collagen, which causes skin to become softer more iridescent. Expect to see more varicose veins on your legs. Tattoos that may have faded over time might become bolder and clearer.
|
||||
|
||||
The removal of testosterone also causes a severe drop in skin oils, particularly on the face and scalp. This results in a significant reduction of acne and/or dandruff.
|
||||
|
||||
### Increased Flexibility
|
||||
|
||||
Testosterone causes water retention in ligaments and tendons, rendering them less stretchable. Removing androgens from the body causes the tendons to release those fluids and regain their elasticity.
|
||||
|
||||
### Slimmer Hands and Wrists
|
||||
|
||||
{!{
|
||||
<div class="gutter flex">
|
||||
{{import '~/img' images.hands className="card" caption="The author's hands. This change occurred over the course of three and a half years."}}
|
||||
</div>
|
||||
}!}
|
||||
|
||||
As the skin begins to soften and slim down, the hands gradually begin the shrink. Without testosterone, less blood flows to the hands, causing further reduction in tissue sizes. Ring size will drop as fat and fluids move off the fingers. Finger length shortens as ligaments thin and stretch.
|
||||
|
||||
### Smaller Feet
|
||||
|
||||
Much like hands, the feet also experience changes in shape. Androgens encourage more blood flow to the feet, and encourage water build up in cartilage. Estrogens allow the ligaments in the foot to stretch more. Collectively this causes the arch of the foot to increase, shortening its total length by as much as two centimeters. Many people report a drop of one to two shoe sizes.
|
||||
|
||||
### Thinner & Softer Fingernails
|
||||
|
||||
Fingernails are made of keratin, and many keratin genes are activated by androgen receptors, thus causing thicker fingernails. The loss of testosterone will make the nails thinner and more prone to breakage.
|
||||
|
||||
### Reduced Body Hair
|
||||
|
||||
Do not expect a total cessation of body hair, once the follicles are made terminal by DHT they remain that way. However, much like fingernails, hair thickness is an expression of keratin genes activated by androgens. Removing testosterone causes the body hairs to become thinner and lighter. Genetics plays a major role in this, however.
|
||||
|
||||
### Changes in Body Temperature Placement
|
||||
|
||||
Androgens encourage extra blood flow to extremities, making them warmer. Because of this, women tend to have warmer core temperatures but lower oral and surface level temperatures. You may see your basal body temperature drop to around 97.6.
|
||||
|
||||
This unfortunately results in a reduced tolerance to cold, so expect to need to layer clothing more frequently, especially since many buildings [set their thermostats for male comfort levels](https://www.popsci.com/study-finds-gender-bias-office-air-conditioning/).
|
||||
|
||||
### Changes in Perspiration Patterns
|
||||
|
||||
With the above shift in temperature distribution, this also results in a significant change in how one sweats. Sweat becomes more of a full body experience, as opposed to largely centered on the head and armpits. Underboob sweat becomes a thing.
|
||||
|
||||
### Reduction and/or Change of Body Odor
|
||||
|
||||
A major component in male body odor is the presence of [the steroid pheromone androstadienone](https://www.sciencedaily.com/releases/2007/09/070916143523.htm) in sweat. Androstadienone is metabolized directly from testosterone, so halting testosterone removes the source. Without it, sweat takes on a much sweeter smell, which is often attributed to feminine odors.
|
||||
|
||||
People taking spironolactone may experience a total cessation of any body odor, due to the way the drug alters cortisol uptake within the body.
|
||||
|
||||
### Reduced Muscle Mass
|
||||
|
||||
Androgens stimulate muscle growth, which is why anabolic steroids (which are literally testosterone) are so common amongst body builders. People running on androgens naturally have more muscle mass, particularly in the upper body, without even having to work out. Removing androgens causes that muscle mass to atrophy and makes it harder to gain muscle. This is a major contributor to the feminine shoulder and neck line, as well as the waist line.
|
||||
|
||||
With this comes a significant loss in strength. Carrying things becomes more difficult, pickle jars become harder to open.
|
||||
|
||||
### Fat Redistribution into Feminine Proportions
|
||||
|
||||
Androgens encourage the body to deposit fats into the abdomen, while estrogen encourages the body to deposit fats into the thighs, buttocks, and hips. Switching profiles causes new fats to be deposited according in the estrogen profile, and fats that were stored while on androgens break down. This produces the illusion of fat migration as the shape of the body changes. The waist line shrinks and defines itself below the ribs, and the belly becomes softer and flatter.
|
||||
|
||||
Because estrogen deposits weight much lower on the body, and the muscle mass in the upper body is lost, this lowers the center of gravity, which alters one's walking gait. It becomes more natural to cantilever the body with the hips while walking, as opposed to the shoulders.
|
||||
|
||||
### Facial Feature Changes
|
||||
|
||||
Along with body fat migration, fat in the face also migrates. The neck, chin and jaw line thin out while the lips and upper cheeks puff up. The brow and upper eye lids lift, exposing more of the eyeball. Changes in skin and musculature around the eye can alter the shape of the eyeball, changing focal depth and altering vision clarity. The color of the eyes may also change and become bolder, as testosterone causes the pigmentation in the iris to fade.
|
||||
|
||||
This is an extremely subtle and slow moving process that takes years, and it is easy to think nothing is changing at all. Take selfies to compare.
|
||||
|
||||
### Changes to Scalp Hair
|
||||
|
||||
With the removal of androgens, blood flow to the scalp increases. Follicles that had been lost to male pattern baldness may reactivate, causing some return of the hair line and a filling in of bald spots. Scalp hair becomes thicker and follicles grow stronger, allowing hair to grow to longer lengths.
|
||||
|
||||
With this thickening, curliness may become more pronounced, and a change in hair color may also occur. You might find your hair taking on a texture more like your mother's than your father's.
|
||||
|
||||
### [Anterior Pelvic Tilt](http://en.wikipedia.org/wiki/Pelvic_tilt)
|
||||
|
||||
As musculature atrophies, ligament flexibility increases, and weight shifts lower on the body, the orientation of the pelvic bone in relation to the spine and femurs rotates forward. Not by much, only about 10-20 degrees, but enough to cause a change in the alignment of the spine and hips, increasing arch of the back and causing the buttocks to jut out more. The added arch to the back can cause a relative drop in total height, between 1 and 2 inches (2-5cm) depending on pelvic shape.
|
||||
|
||||
Note, this is NOT the same as the [hip rotation](https://youtu.be/OROoZzoVwfk?t=12) that occurs in AFAB puberty and during pregnancy. That is the result of migration of bone cells, altering the shape of the pelvic bone itself. **However**, hip rotation *can* occur if the person is young enough to still be within initial puberty, where the body is producing elevated human growth hormone. There have also been examples of hip rotation happening over long periods of time in trans elders. In 2017 an 80 year old trans woman reported on reddit that over the course of her 30 years on HRT, her doctor observed changes in her pelvis consistent with female hip rotation.
|
||||
|
||||
### Reduced Tolerance of Caffeine, Alcohol, and/or Psychotropics
|
||||
|
||||
Less body mass means less blood to dilute chemicals into. Losing testosterone also means a slower metabolic rate, decreasing the speed at which toxins are reduced from the blood stream. Some anti-androgens also put strain on the liver, further reducing how quickly chemicals are processed.
|
||||
|
||||
### Mental Changes
|
||||
|
||||
As covered in the [Biochemical Dysphoria]() section, brains can be wired for a certain hormone profile, and running on the wrong profile is like using a laptop with low batteries or an overheated processor. Starting HRT almost universally results in a cessation of depersonalization and derealization (DPDR) symptoms within the first two weeks. A mental fog lifts, and it becomes easier to concentrate on complex concepts (assuming you don't also have other mental processing difficulties such as ADHD).
|
||||
|
||||
##### ADHD
|
||||
|
||||
If you have ADHD, there may be some changes in your symptoms. Androgens amplify [dopamine](https://en.wikipedia.org/wiki/Dopamine) receptor function, so reducing testosterone can reduce the activation potential for dopamine in the brain. Dopamine is a key neurotransmitter in the behavior of [working memory](https://en.wikipedia.org/wiki/Working_memory), the short-term memory of the brain. Less working memory means you become more prone to distractions and have more difficulty maintaining [cognitive load](https://en.wikipedia.org/wiki/Cognitive_load).
|
||||
|
||||
The good news is that estradiol prompts the brain to produce MORE dopamine.
|
||||
|
||||
{!{ <div class="gutter flex" style="justify-content: flex-end"><div class="card"><div class="card-body"><h4 class="card-title">Authors Note:</h4> }!}
|
||||
|
||||
There is a known problem with Spironolactone hampering working memory due to it's affects on mineralcorticoids. This can significantly worsen ADHD issues and make it much harder to maintain focus or be aware of your surroundings. I was involved in a car accident in 2017 that I blame on spiro fog.
|
||||
|
||||
{!{ </div></div></div> }!}
|
||||
|
||||
##### Emotional Expansion
|
||||
|
||||
The alleviation of DPDR almost universally is accompanied with a much broader capacity for emotion and expression. The stoicism and dissociation lifts and emotions land with much greater intensity. Highs are higher and lows are lower. Those who may have been unable to cry, before transition, gain it back, both for sadness and for joy.
|
||||
|
||||
Unfortunately this also means that if you had trauma from events earlier in life (and who doesn't), you may start to experience PTSD episodes. This is why it is good (and in some places, required) to have a therapist.
|
||||
|
||||
##### Mood Swings
|
||||
|
||||
As estrogen levels fluctuate between doses you may experience noticeable and sometimes dramatic shifts in your mood. Unexplained crying happens; PMS rage happens; be ready for it.
|
||||
|
||||
##### Appetite
|
||||
|
||||
Many people report being unable to eat as much as they could pre-transition. The loss of lean muscle in the arms and shoulders means that the body has a reduced capacity for burning lipids, and as such the fullness sensation occurs earlier.
|
||||
|
||||
However, progesterone increases mitochondrial function within the body, boosting metabolic rate. This can cause an increase in appetite as the body attempts to replenish calories burned.
|
||||
|
||||
That said, you may find yourself unable to eat *as much* food as you could before. Many report that they become full/satisfied sooner than before.
|
||||
|
||||
##### Sleep
|
||||
|
||||
Many people report having better sleep patterns after starting HRT. This is likely a factor of the alleviation of DPDR, as it seems to occur in both AMAB and AFAB trans people. That said, initiating progesterone can *significantly* improve sleep, allowing for deeper sleep and more dreaming.
|
||||
|
||||
##### Extroversion
|
||||
|
||||
It's extremely common for trans people of all types to find themselves much more sociable post-transition. This may not actually be a factor of hormone therapy, however, an simply be a result of no longer having to suppress large portions of their personality.
|
||||
|
||||
### Sensory Enhancements
|
||||
|
||||
Transgender HRT has [been shown several times](https://academic.oup.com/cercor/article/28/5/1582/3064956) to cause changes in the distribution of gray matter and white matter within the brain for trans people on both forms of HRT. New structures and neuro-pathways are formed as a result of the shift in hormone profiles, and this results in changes of sensory perception. These are some of the changes that have been observed and reported, but it is is not clear if this is a function of the hormones themselves, or a factor of the brain receiving the hormones it is wired for.
|
||||
|
||||
- **Improved sense of smell**, especially of other bodies. Human sweat becomes very discernible, even overpowering at times.
|
||||
- **Improved color perception**. Colors may become bolder, richer.
|
||||
- **Improved spatial awareness**. Many trans people experience poor proprioception and a tendency towards clumsiness that goes away after starting HRT.
|
||||
- **Changes in perception of taste**. Certain foods become more or less palatable; Cilantro, for example, may become more or less soapy. Increased tolerance of capsaicin (spicy peppers). Chocolate and wine become more flavorful.
|
||||
|
||||
Users of Spironolactone often develop strong cravings for foods high in salt, such as pickles, olives, or potato products. This is because Spiro is a potassium sparing diuretic which causes you to pee out all your sodium. The brain creates cravings to encourage you to replace that sodium.
|
||||
|
||||
### Spatial Shift, Reduced Confidence
|
||||
|
||||
There is a very frequently reported experience of feeling smaller within the world, even when wearing heels. People taller than you seem to tower over you, and spaces feel larger.
|
||||
|
||||
People have also reported a tendency to be less prone to start arguments, an a desire to avoid confrontation rather than create it. Testosterone has been shown to increase a persons sense of confidence, and removing it has the opposite affect.
|
||||
|
||||
|
||||
### Genital Changes
|
||||
|
||||
{!{
|
||||
<div class="gutter flex">
|
||||
{{import '~/img' images.homology link='https://www.vielma.at/' }}
|
||||
</div>
|
||||
}!}
|
||||
|
||||
All genitalia are constructed from the same tissues, they are merely organized differently during gestation. Much of the behavior of these tissues is regulated by the hormones ones body runs on. Skin secretions, textures, sensitivity and erectile behavior are all hormonal expressions. Which means that when you remove androgens and add estrogens, these tissues start acting like they are in the shape of a vulva, even though they aren't.
|
||||
|
||||
##### Increased Sensitivity
|
||||
|
||||
The skin on the glans and shaft becomes much thinner and fragile, more prone to tearing and irritation, while also becoming *significantly* more sensitive to touch. The entire organ also becomes much more sensitive to pressure, and vibration becomes a better form of stimulation over stroking, which may become painful.
|
||||
|
||||
#### Moisture and Feminine Odor
|
||||
|
||||
The skin along the shaft begins to secret the same fluids as the vaginal canal, particularly during arousal (yes, trans girls get wet). These fluids encourage the development of the same microbiome that develops within the vaginal canal. The combination of these factors means that odor (and taste) of the penis changes to align more to that of a vulva.
|
||||
|
||||
##### Color and Texture Changes
|
||||
|
||||
The scrotum is an analog of the outer and inner labia, and softens to take on a softer, more velvety texture, extending down into the perineum. The skin along the perineal raphe (the vertical line where the vulva opening had been before the scrotum formed) will also darken. Some people experience a kind of striping pattern along the scrotum.
|
||||
|
||||
##### Fewer Erections
|
||||
|
||||
Without free floating testosterone, the levels of [DHT](https://en.wikipedia.org/wiki/Dihydrotestosterone) in the bloodstream drop significantly. DHT plays a major role in the stimulation of random erections during sleep through the enlargement of the prostate, and these erections are what is responsible for the maintenance of the erectile tissue. Without DHT, the prostate shrinks again, and random erections cease (no more morning wood).
|
||||
|
||||
However this means that the erectile tissue will begin to atrophy. Prolonged atrophy will result in shrinkage of the entire organ, for better or worse. The shape of the penis changes as this occurs, often becoming more conical. The glans is the first part to shrink and may lose the ability to become rigid. Penetrative sex may become more difficult, and erections themselves may become painful.
|
||||
|
||||
This can be countered by regularly inducing erections, but that may become more and more difficult as time goes on.
|
||||
|
||||
##### Clear Ejaculate
|
||||
|
||||
The majority of the liquid that makes up ejaculate originates in the prostate. It is a completely clear fluid, with a slimy texture. The white color and stickiness that is usually attributed to male ejaculate is caused by semen and seminal fluid from the testicles. The production of both semen and seminal fluid is a product of testicle function, so as the testicles shutdown (either because of anti-androgens or from estrogen dominance), these fluids halt, leaving only the prostate fluid.
|
||||
|
||||
Some people lose even that, and stop having any emissions at all during orgasm.
|
||||
|
||||
Needless to say, this comes with sterility. Contrary to what some sources report, this is NOT permanent, and many people have been able to restore testicle functionality by halting hormone therapy, either for detransition or for reproductive purposes.
|
||||
|
||||
##### Testicle Atrophy
|
||||
|
||||
Once the testes have stopped functioning, the cells start to atrophy, shrinking over time. This atrophy may be accompanied with pain, sometimes in the form of a soreness or a dull throbbing sensation, or sometimes as registering as little sparks of pain that travel along the perineal nerve from the testicles down to the rectum.
|
||||
|
||||
### Sexual Changes
|
||||
|
||||
Initial start of HRT may result in a total loss of sex drive as testosterone levels plummet. This can last 3-12 months, and in some cases doesn't return at all. Starting progesterone often serves as catalyst for its return. If/when sex drive comes back, the new libido [may be a completely different experience](https://curvyandtrans.com/p/5BF1EA/libatious-libidos) that one may not recognize at first.
|
||||
|
||||
##### Heightened Erogenous Zones
|
||||
|
||||
{!{
|
||||
<div class="gutter flex">
|
||||
<div class="card"><div class="card-body"><h4 class="card-title">Human Erogenous Zones:</h4>
|
||||
{{import '~/img'
|
||||
images.erogenous
|
||||
link='https://www.researchgate.net/publication/301509880_Topography_of_Human_Erogenous_Zones#pf19'
|
||||
caption='Source: <a href=\"https://link.springer.com/article/10.1007/s10508-016-0745-z\">Topography of Human Erogenous Zones</a>'
|
||||
}}
|
||||
</div></div>
|
||||
</div>
|
||||
}!}
|
||||
|
||||
The entire body becomes more responsive to touch, and with that unlocks stronger erogenous zones. Breasts, abdomen, inner thighs and neck, in particular, become more arousal inducing.
|
||||
|
||||
##### Orgasm
|
||||
|
||||
Orgasm changes significantly, both in the way it builds and how it is experienced (see link above), but additionally, if one is lucky, they will gain the ability to become multi-orgasmic with no refractory period. The cost of this is that orgasm may become harder to achieve, and one has to re-learn how to reach it. It also becomes easier to reach with a partner, which may have been the opposite before.
|
||||
|
||||
##### Attraction
|
||||
|
||||
It is [not at all unheard of](https://www.them.us/story/sexual-attraction-after-transition) for a transgender person to experience a change in their sexual orientation with transition. This is almost always the result of the removal of self-imposed mental barriers, but hormone therapy often plays a role *in* that removal. In most cases this simply involves an expansion of ones attraction, from monosexual to bi/pansexual, but some people also discover that their attraction was largely rooted in self-interest and that their true attraction is reversed.
|
||||
|
||||
### Cyclical Period-like Symptoms
|
||||
|
||||
Obviously, we do not mean blood flow, that would be ludicrous. Symptoms vary greatly (just as they do in cisgender women) and typically last for 2-4 days, repeating every 26-32 days (though some report experiencing it bi-weekly). This happens independent of medication dosing schedules. The use of a period tracker app like Clue can reveal the pattern.
|
||||
|
||||
- Cramping in the intestine and abdominal muscles, ranging from a slight flutter in the gut to strong painful spasms.
|
||||
- Bloating and water retention
|
||||
- Gas, diarrhea and other intestinal issues.
|
||||
- Emotional instability, mood swings and irrational thoughts
|
||||
- Heightened depression and dysmorphia
|
||||
- Depersonalization or dissociation.
|
||||
- Increased dysphoria
|
||||
- Irritability (PMS)
|
||||
- Muscle and joint aches and pains
|
||||
- Breast engorgement and nipple tenderness
|
||||
- Acne
|
||||
- Fatigue
|
||||
- Appetite changes, spontaneous cravings (see: chocolate cravings)
|
||||
- Spontaneous shifts in libido
|
||||
- Changes in genital odor
|
||||
|
||||
No, there have not yet been studies on this yet, but it is reported by far, **far** too many individuals to be an anomaly (including by yours truly), and has been confirmed by multiple people's own doctors. There is also precedent of this happening with cisgender women who have had hysterectomies (I personally know two cisgender women who have cycles but do not menstruate, without any medical intervention).
|
||||
|
||||
Running on estrogen and progesterone activates a gene sequence which instructs the hypothalamus to attempt to cycle ovary and uterine behavior just as it does in female assigned individuals, regardless of the absence of ovaries or a uterus. This cycle affects numerous organs and subsystems in the body, causing the release of a variety of different hormones and enzymes that can affect function and even behavior.
|
||||
|
||||
A more thorough explanation of this will be coming in a later update to the site.
|
||||
212
public/gdb/es/segunda-pubertad-masc.md
Normal file
212
public/gdb/es/segunda-pubertad-masc.md
Normal file
@ -0,0 +1,212 @@
|
||||
---
|
||||
date: "2020-01-26T20:41:55.827Z"
|
||||
title: "Androgenic Second Puberty 101"
|
||||
description: "What to expect from masculinizing HRT"
|
||||
preBody: '_disclaimer'
|
||||
siblings:
|
||||
prev: /gdb/es/hormonas
|
||||
prevCaption: How Hormones Work
|
||||
next: /gdb/es/segunda-pubertad-fem
|
||||
nextCaption: Estrogenic Second Puberty
|
||||
classes:
|
||||
- gdb
|
||||
|
||||
tweets:
|
||||
- '1374054574579798016'
|
||||
- '1374039857773875201'
|
||||
- '1374040823382347778'
|
||||
- '1374053191445270534'
|
||||
- '1374060995778318347'
|
||||
- '1374048251180027920'
|
||||
- '1374076480985128970'
|
||||
- '1374094470753423360'
|
||||
---
|
||||
|
||||
# Androgenic Second Puberty 101
|
||||
|
||||
## What to expect from Masculinizing HRT
|
||||
|
||||
This is a compilation of reported medical transition changes collected from testimonials of AFAB trans people taking testosterone hormone therapy. This information is gathered from social media and chat rooms. Yes, that means this is all anecdotal, but historically, most of transgender medical study is anecdotal because no one wants to fund transgender medical research.
|
||||
|
||||
**Note that this is a list of _possible_ changes. There is no guarantee that every person on masculinizing HRT will experience all of these. Your age, genetics, medical history, degree of feminization from natal puberty, and hormone regimen can all have impacts on results. There is also just a degree of randomness -- every body is different -- and some things can take years to appear.**
|
||||
|
||||
### Voice Drop
|
||||
|
||||
Androgens cause the tissue that comprises the vocal chords to thicken and harden, permanently lowering the pitch of the voice. This is not a very fast change, but rather incremental over the first few years. Some people do not experience any voice change at all, it varies person to person. The change will not be drastic, if you are a soprano you are not going to become a bass, but it could bring you down to a contralto or tenor.
|
||||
|
||||
This does *not* mean that your voice will automatically become read as male. Pitch is only a piece of how people gender voice, and the way you speak plays a much larger role. Vocal training will be needed to amplify resonance and change speaking style.
|
||||
|
||||
### Changes in Body Temperature Placement
|
||||
|
||||
{!{ <div class="gutter">{{import '~/tweet' ids=[
|
||||
'1374039857773875201'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
Androgens encourage extra blood flow to the extremities, making them warmer. Because of this, men have cooler cores but warmer oral and surface level temperatures. You may see your basal body temperature increase. The net result is that you will *feel* warmer, and likely will not be able to layer clothing as much as previously possible. If you live in cold climates, exposing your calves can help to dissipate heat without chilling you too severely.
|
||||
|
||||
This change often comes fairly early on; expect night sweats while your system gets used to it.
|
||||
|
||||
### Changes in Perspiration
|
||||
|
||||
With the above shift in temperature distribution, this also results in a significant change in how one sweats. Sweat will pool on the head, back and armpits. You'll also likely sweat more often, so keep water handy.
|
||||
|
||||
### Body Odor
|
||||
|
||||
Often one of the first things to change: sweat and general body odor will become much stronger, especially during exercise. The smell will take on a sour, muskier smell. Tends to even out over time.
|
||||
|
||||
### Body Hair, Everywhere
|
||||
|
||||
Androgens significantly increase the presence of body hair on the legs, groin, buttocks, chest, back and arms. Hair will grow in thicker, longer and darker. This will likely happen well before facial hair growth, which can take over a year to start. Rogaine / Monoxidil can help with that, but be careful as it is poisonous if ingested, especially to cats.
|
||||
|
||||
### Male Pattern Baldness
|
||||
|
||||
MPD is caused by [Dihydrotestosterone](https://en.wikipedia.org/wiki/Dihydrotestosterone) (DHT), an androgen which metabolizes from Testosterone. Having more T in your body means more DHT can form, and the gene that contributes to MPD causes the hair follicles on the scalp to receive less blood, choking them out until the follicles die. There will likely be *some* loss of hair line eventually, no matter what, but if there is a history of baldness among the men in your family, then you can expect to see that as well. Again, Rogaine can help with this.
|
||||
|
||||
The synthetic androgen [Nandrolone](https://en.wikipedia.org/wiki/Nandrolone) does not metabolize into DHT and may be a viable alternative in place of direct Testosterone if hair loss is a concern. However, DHT is important for genital growth, so this is a double-edged sword.
|
||||
|
||||
### Thicker and Oilier Skin
|
||||
|
||||
Testosterone promotes the thickening and toughening of the epidermis, causing skin to become coarser. As estrogen levels fall, the body will produce less collagen. This causes the skin to become tougher and drier (especially in the knees and elbows). Veins on the hands, arms, and legs may become more pronounced, but not varicose.
|
||||
|
||||
Expect your face and scalp to become oilier. Acne is likely to be a problem, and not just on the face. This tends to be worst immediately after dosing. This will generally improve after the first few years.
|
||||
|
||||
### Larger Hands / Feet
|
||||
|
||||
Over long periods of time (3-5 years) the hands may become tougher and more calloused. You may need to increase your ring size eventually.
|
||||
|
||||
Testosterone also causes ligaments and tendons to retain more water, altering their flexibility. Over time this can result in an increase in foot size as the arch of the foot lowers.
|
||||
|
||||
### Thicker and Stronger Nails
|
||||
|
||||
Both fingernails and toenails will grow thicker over time as keratin levels rise due to the presence of androgens.
|
||||
|
||||
### Increased Muscle Mass
|
||||
|
||||
Androgens stimulate muscle growth, which is why anabolic steroids (which are literally testosterone) are so common amongst body builders. The body will naturally gain more muscle without even having to exercise, but *with* exercise there can be substantial gains, particularly in the arms and shoulders. Beware, you won't know your own strength at first.
|
||||
|
||||
Added lean muscle in the upper body redefines the shoulder and neck line, creating a more masculine silhouette. It also improves the body's ability to process lipids, making weight loss easier.
|
||||
|
||||
### Fat Redistribution
|
||||
|
||||
Where estrogen encourages the body to deposit fats into the thighs, buttocks, and hips, androgens encourage the body to deposit fats largely into the abdomen. Starting testosterone will encourage your body to follow the androgen pattern, so you can expect new weight to deposit into your belly, while weight loss will take away from all over. Fat in the breasts, thighs and buttocks will slowly shift away as muscle builds, but this may take a long time.
|
||||
|
||||
### Facial Feature Changes
|
||||
|
||||
Along with body fat migration, fat in the face also moves. The neck, chin and jaw line will fill out while the lips and upper cheeks shrink. The color of the eyes may also change and become fainter in the long term, as testosterone causes the pigmentation in the iris to fade.
|
||||
|
||||
This is and extremely subtle and slow moving process that takes years, and it is easy to think nothing is changing at all. The greatest shifts seem to happen in years 3 and 4. Take selfies to compare.
|
||||
|
||||
|
||||
### Increased Tolerance of Caffeine, Alcohol, and/or Psychotropics
|
||||
|
||||
More mass means more blood to dilute chemicals into. Increasing testosterone also means a higher metabolic rate, increasing the speed at which toxins are removed from the blood stream.
|
||||
|
||||
### Mental Changes
|
||||
|
||||
As covered in the [Biochemical Dysphoria]() section, brains can be wired for a certain hormone profile, and running on the wrong profile is like using a laptop with low batteries or an overheated processor. Starting HRT almost universally results in a cessation of depersonalization and derealization (DPDR) symptoms within the first two weeks. A mental fog lifts, and it becomes easier to concentrate on complex concepts (assuming you don't also have other mental processing difficulties such as ADHD).
|
||||
|
||||
##### ADHD
|
||||
|
||||
If you have ADHD, there may be some changes in your symptoms. Androgens amplify [dopamine](https://en.wikipedia.org/wiki/Dopamine) receptor function, so increasing testosterone can improve the activation potential for dopamine in the brain. Dopamine is a key neurotransmitter in the behavior of [working memory](https://en.wikipedia.org/wiki/Working_memory), the short-term memory of the brain. More working memory means you may become less prone to distractions and have an easier time maintaining [cognitive load](https://en.wikipedia.org/wiki/Cognitive_load).
|
||||
|
||||
*However*, estradiol encourages the production of dopamine, so as estrogen levels fall there will be less dopamine for the brain to work with. Your symptoms worsen, not improve.
|
||||
|
||||
##### Emotional Expansion
|
||||
|
||||
The alleviation of DPDR almost universally is accompanied with a much broader capacity for emotion and emotional regulation. Emotions become somewhat more controllable and suppressible, less likely to overwhelm on the spot. *Please note: suppressing emotions is a very quick way to develop trauma.*
|
||||
|
||||
However, the ability to express them may become reduced. Some people lose the ability to cry after starting on testosterone, but this is *not* a universal experience and may be tied into how strong your T dose is. The reasons behind this aren't well known, although some studies have found that androgens alter function in parts of the brain connected to emotional processing. If you do lose the ability to cry, it may return in time as your brain become more acclimated and you come out of second puberty.
|
||||
|
||||
{!{ <div class="gutter flex" style="justify-content: flex-end">{{import '~/tweet' ids=[
|
||||
'1374060995778318347'
|
||||
'1374070062236246022'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
Emotional dis-regulation occurs the most commonly before and immediately after dosing (injections or gel) and results in reduced patience, increased aggression.
|
||||
|
||||
##### Increased Appetite / Eating Capacity
|
||||
|
||||
You are going to be hungry. Testosterone cranks the body's metabolism up significantly, and increased muscle mass means there is more to feed, so you will burn calories faster.
|
||||
|
||||
##### Sleep
|
||||
|
||||
Some people report problems with insomnia and having fewer memorable dreams. This is far from a universal, however.
|
||||
|
||||
{!{ <div class="gutter flex" style="justify-content: flex-end">{{import '~/tweet' ids=[
|
||||
'1374076480985128970'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
##### Confidence
|
||||
|
||||
Testosterone is known to induce a strong sense of self-confidence in people. Problems seem less significant, self-esteem is stronger, fewer anxieties. Many people report a tendency to be more prone spark arguments, and more willing to speak out in the face of conflict and self advocate. This does *not* mean more hostile or argumentative, simply that ones tolerance for bullshit is lower.
|
||||
|
||||
##### Extroversion
|
||||
|
||||
It's extremely common for trans people of all types to find themselves much more sociable post-transition. This may simply be a result of no longer having to suppress large portions of their personality, but the aforementioned confidence also plays a role.
|
||||
|
||||
### Genital Changes
|
||||
|
||||
{!{
|
||||
<div class="gutter flex flex-center">
|
||||
{{import '~/img' images.homology link='https://www.vielma.at/' }}
|
||||
</div>
|
||||
}!}
|
||||
|
||||
All genitalia are constructed from the same tissues, they are merely organized differently during gestation. Much of the behavior of these tissues is regulated by the hormones ones body runs on. Skin secretions, textures, sensitivity and erectile behavior are all hormonal expressions. Which means that when you add androgens, these tissues start acting like they are in the shape of a penis and scrotum, even when they aren't.
|
||||
|
||||
##### Bottom Growth
|
||||
|
||||
DHT (mentioned above) plays a critical role in the development of the erectile tissue within the genitals. As DHT levels rise with the increase in Testosterone, this will cause the Skene's Gland (sometimes referred to as the female prostate) to swell. This will induce random erections within the clitoris, causing the erectile tissue to grow. The amount of growth varies from person to person, but 1-3 inches is common.
|
||||
|
||||
{!{ <div class="gutter">{{import '~/tweet' ids=[
|
||||
'1374094470753423360'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
The clitoral hood and labia will become drier and thicker over time, and the inner labia may also start to grow hair. Self lubrication may reduce substantially, and over time penetration may become painful. Use more lube to avoid tearing and bleeding.
|
||||
|
||||
##### Increased Emissions During Climax
|
||||
|
||||
With the swelling of the prostate comes more prostate fluid. If you weren't a squirter before, you may become one now.
|
||||
|
||||
##### Changes in Sensitivity and Response
|
||||
|
||||
Erogenous stimulation may become more focused on the head of the clitoris and in stroking of the shaft.
|
||||
|
||||
##### Atrophy
|
||||
|
||||
Vaginal and uterine atrophy often happens within the first five years, and a hysterectomy may become necessary. Signs of atrophy include a deep throbbing in the lower abdomen and painful cramping without other period symptoms, particularly following intercourse. Vaginal atrophy can be avoided through the use of the same vaginal dilators that AMAB trans people use following vaginoplasty.
|
||||
|
||||
##### Increased Sex Drive
|
||||
|
||||
{!{ <div class="gutter flex flex-end">{{import '~/tweet' ids=[
|
||||
'1374040823382347778'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
Libido will almost certainly go through the roof for the first year or two, the strongest immediately following dosing. May find yourself more assertive during sex and more prone to being dominant and/or a top.
|
||||
|
||||
##### Orgasm
|
||||
|
||||
{!{ <div class="gutter">{{import '~/tweet' ids=[
|
||||
'1374053191445270534'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
The "shape" of ones orgasm can change. Rather than a cascade, it strikes like an explosion from the groin.
|
||||
|
||||
##### Attraction
|
||||
|
||||
Testosterone has been shown to increase arousal from visual stimuli. As such, you may *notice* people of your sexual preference much quicker, especially if you are gynephilic (attracted to the feminine shape).
|
||||
|
||||
### Cessation of Menstruation
|
||||
|
||||
The increase of androgens within the body causes the hypothalamus to down-regulate production of the hormones which control the ovaries. This will reduce total estrogen available, and may halt ovulation. Without ovulation and with lower FSH levels, the uterus will be less inclined to build up and release a lining, causing the cessation of blood flow.
|
||||
|
||||
|
||||
{!{ <div class="gutter">{{import '~/tweet' ids=[
|
||||
'1374054574579798016'
|
||||
] tweets=meta.tweets className="hide-mentions" }}</div> }!}
|
||||
|
||||
|
||||
You may still experience other period symptoms, however, as the hypothalamus can continue to express other aspects of the monthly cycle. This can even continue following a total hysterectomy, although it is not common.
|
||||
|
||||
**This does *not* mean that you are infertile, however.** Ovulation can still occur even if you are not menstruating. Additionally, halting testosterone will make the old orbs wake up, they do not die.
|
||||
|
||||
@ -63,7 +63,7 @@
|
||||
|
||||
<div class="top-nav">
|
||||
<ul class="top-nav-inner">
|
||||
<li><a href="/gdb/" class="top-nav-item dropdown-toggle" id="nav-gdb" data-toggle="dropdown" data-flip="false" aria-haspopup="true" aria-expanded="false">The Gender Dysphoria Bible</a>{{import '/public/_gdb-menu'}}</li>
|
||||
<li>{{import '/public/_gdb-menu'}}</li>
|
||||
<li><a href="/tweets/" class="top-nav-item" title="Trans Twitter Topics"><img src="/images/transtwitter.png" width="24" height="24" alt=""></a></li>
|
||||
<li class="disposable"><a href="https://github.com/GenderDysphoria/GenderDysphoria.fyi/issues" class="top-nav-item">{{icon 'brands/github'}}</a></li>
|
||||
<li class="disposable"><a href="https://patreon.com/curvyandtrans" class="top-nav-item" title="Patreon">{{icon 'brands/patreon'}}</a></li>
|
||||
|
||||
Loading…
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Reference in New Issue
Block a user